Publications

  1. Nicholas DA*, Proctor E*, Jones A, Agrawal M*, Belkina A, Panneerseelan-Bharath L, Raval F, Ip B, Zhu M, Cacicedo J, Persky L, Sainz-Rueda N, Habib C, Corkey B, Apovian CM, Kern P, Lauffenburger D, Nikolajczyk BS. (2019) Fatty Acid Metabolites Combine with Reduced β oxidation to activate Th17 Inflammation in Human Type 2 Diabetes. Cell Metabolism 
     Featured in Nature Reviews Endocrinology. Morris A. Glucose isn’t  always to blame. 2019 Aug
     Featured in Science Daily. University of Kentucky. “What drives inflammation in type 2 diabetes? Not glucose, says new research.” 2019 Aug
  2. Kim T, Li D, Terasaka T, Nicholas DA, Knight VS, Yang J, Lawson MA. (2019) SRXN1 is Necessary for Resolution of GnRH-induced Oxidative Stress and Induction of Gonadotropin Gene Expression.
    Endocrinology
  3. Terasaka T, Kim T, Dave H, Gangapurkar B, Nicholas DA, Muñoz O, Terasaka E, Li D, Lawson MA. (2019) The RNA-binding Protein ELAVL1 Regulates GnRH Receptor Expression and the Response to GnRH.  Endocrinology
     Featured in Endocrinology. MacNicol, A. ELAVL1 Elevates Insights: The Ups and Downs of Regulated mRNA Translation in the Control of Gonadotropin Release. 2019 Oct
  4. Nicholas, D.; Glasgow, S.; Firek, A.; Payne, K.J.; Langridge, W.; De Leon, M. (2017). Palmitic Acid is a ligand for Toll-Like Receptor 4. Plos One
  5. Nicholas, D.; Proctor, E.; Raval, F.; Ip. B.; Habib, C.; Ritou, E.; Grammatopoulos, T.N.; Steenkamp, D; Dooms, H.; Apovian, C.M.; Lauffenburger, D.; Nikolajczyk, B.S. (2017) Advances in the quantification of mitochondrial function in primary human immune cells through extracellular flux analysis. Plos One
  6. Nicholas, D.; Andrieu, G; Strissel, K.J.; Nikolajczyk B.S.; Denis, G.V. 2016. BET bromodomain proteins and epigenetic regulation of inflammation: implications for type 2 diabetes and breast cancer. (2016) Cell Mol Life Sci.
  7. Strissel, K.J.; Nicholas, D.; Castagne-Charlotin, M.; Ko, N.; and Denis, G.V. (2016) Barriers to Obtaining Biospecimens from African American Women for the Advancement of Cancer Research. Clin Med Insights Womens Health. 9(Suppl 1):57-61
  8. Nicholas, D.; and Nikolajczyk (2016). B cells shed light on diminished vaccine responses in obesity. Obesity. 24(3):551.
  9. Kim, N.; Mbongue, J.; Nicholas, D.; Umezawa K.; Firek A., and Langridge W.H.R. (2016) Chimeric Vaccine Stimulation of Human Dendritic Cell Indoleamine 2, 3-Dioxygenase Occurs via the Non-canonical NF-κB Pathway. Plose One. 10 (2), e0118562
  10. Nicholas, D.; Salto L.M.; Boston A,M.; Beeson L.; Firek A.; Casiano C.A.; Langridge W.H.R.; Cordero-MacIntyre Z.; and DeLeon M. (2015). Identification of Anti-Long Chain Saturated Fatty Acid IgG Autoantibodies in Serum of Patients with Type 2 Diabetes. Mediators Inflamm. 2015;2015:196297.
  11. Mbongue, J.; Nicholas, D.; Torrez, TW.; Kim, N.; Firek A., and Langridge W.H.R. (2015) The Role of Indoleamine 2, 3-Dioxygenase in Immune Suppression and Autoimmunity. Vaccines (Basel). 2015 Sep 10;3(3):703-29.
  12. Mbongue, J.; Nicholas, D.; Zhang K.; Kim, N.; Hamilton B.N.; Larios M.; Umezawa K.; Firek A., and Langridge W.H.R. (2014) Induction of Indoleamine 2, 3 Dioxygenase in Human Dendritic Cells by a Cholera Toxin B Subunit – Proinsulin Fusion Protein Vaccine. Plose One. 10 (2), e0118562
  13. Nicholas, D.; Hui Tang H.; Zhang Q.; Rudra J.; Xu F.; Langridge, W.; Zhang K. 2014. Quantitative Proteomics Reveals a Role for Epigenetic Reprogramming During Human Monocyte Differentiation. Mol Cell Proteomics mcp.M113.035089.
  14. Mbongue, J.; Nicholas, D.; Firek, A.; Langridge, W. 2014. The role of dendritic cells in tissue-specific autoimmunity. J Immunol Res. 2014;2014:857143
  15. Odumosu, O.; Nicholas, D.; Payne, K.; Langridge, W. 2011. Cholera Toxin B Subunit Linked to Glutamic Acid Decarboxylase Suppresses Dendritic Cell Maturation and Function. Vaccine. 29(46):8451-8458.
  16. Nicholas, D.; Odumosu, O.; Langridge, W. 2011. Autoantigen Based Vaccines for Type 1 Diabetes. Discovery Medicine,(59):293-301
  17. Odumosu, O.; Nicholas, D.; Yano, H.; Langridge, W. 2010. AB Toxins: A Paradigm Switch from Deadly to Desirable. Toxins. 2, 1612-1645.